Photodynamic Therapy (PDT)
A treatment that combines intravenous photosensitizer injection with specific-wavelength laser activation to selectively close abnormal neovascularization.
Photodynamic therapy (PDT) involves intravenous injection of the photosensitizer verteporfin (Visudyne), which accumulates in choroidal neovascularization. A 689nm non-thermal laser then activates the drug in the lesion area, generating reactive oxygen species that selectively damage neovascular endothelial cells, causing vessel closure. PDT minimally affects surrounding normal tissue and is suitable for specific AMD subtypes (polypoidal choroidal vasculopathy/PCV) and certain macular neovascularization. Strict light avoidance for 48 hours post-treatment is required.
Quick Reference
Treatment
20 mins – 30 mins
Observation
1 hours – 2 hours
Est. Cost
¥1,170.5 – ¥2,633.63
Department
Ophthalmology
Who Is This For
Is Photodynamic Therapy (PDT) Right for You?
Good Candidates
- Polypoidal choroidal vasculopathy (PCV)
- Wet AMD with inadequate anti-VEGF response
- Certain types of choroidal neovascularization
- Chronic central serous chorioretinopathy (CSC)
May Not Be Suitable
- Verteporfin allergy
- Severe hepatic insufficiency (drug is hepatically metabolized)
- Porphyria patients
Step-by-Step Process
How Photodynamic Therapy (PDT) Works
IV access establishment
Establish IV access; slowly infuse verteporfin (6mg/m² BSA) over 10 minutes.
Drug distribution period
Wait 5 minutes after infusion for drug concentration in neovascularization.
Laser irradiation
Apply 689nm laser to the lesion area through slit-lamp and contact lens for 83 seconds (spot size covering lesion extent).
Light avoidance instructions
Instruct patient on strict 48-hour avoidance of sunlight and bright light, including skin exposure.
Evaluation typically every 3 months; repeat treatment based on angiography and OCT findings. Often combined with anti-VEGF injections.
Cost Information
Cost Estimate for Photodynamic Therapy (PDT)
Estimated Price Range
¥1,170.5 – ¥2,633.63
What's Included
Public tier-3A International Medical Department: approximately ¥8,000-13,000 per session (including verteporfin); premium private eye centers: approximately ¥13,000-18,000 per session. Verteporfin is an imported drug accounting for the majority of the cost.
Before Your Visit
What to Prepare
Required Tests & Examinations
If you already have recent valid test results, bring the reports. If not, these assessments can usually be completed in China before the procedure.
FFA and ICG angiography
OCT examination
Visual acuity testing
Liver function tests
Documents & Materials to Bring
Required to Bring
Passport and valid visa
Previous angiography records
Wide-brimmed hat and sunglasses (for post-treatment light avoidance)
Companion & Support
Accompaniment needed on treatment day due to light restriction limiting mobility.
After Treatment
Recovery & Follow-Up
Strictly avoid sunlight and bright light for 48 hours (including indoor bright light)
Wear wide hat, dark sunglasses, gloves, and long sleeves outdoors
Gradual return to normal light exposure after 48 hours
Mild injection site discomfort possible
Seek immediate care if vision declines
Follow-Up Schedule
Follow-up at 1 week, 1 month, and 3 months. May need repeat treatment based on disease status.
Related Conditions
Conditions This Procedure Treats
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Frequently Asked Questions
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